Applying concepts of chemistry and physics to understand biology.

 

We use a wide variety of experimental and computational approaches to explore structure-function relationships in SIKE and a number of its homologs and interaction partners as well as several oligomeric dehydrogenases that show complex allosteric interactions

 

 
 
 Allosteric Regulation of Oligomeric Dehydrogenases

Allosteric Regulation of Oligomeric Dehydrogenases

 Structure & Interactions of SIKE

Structure & Interactions of SIKE